Assessment of Mean Corpuscular Volume as a Surrogate Marker for Detecting Early Iron Deficiency among School Children

نویسندگان

  • AE Eldesouky
  • ME Awad
  • SM Abdelsalam
چکیده مقاله:

Background: The aim of the present study was to assess the mean corpuscular volume (MCV) as a surrogate marker for detecting early iron deficiency prior to definitive investigation and treatment. Materials and Methods: This study was done on one hundred students in Swada Preparatory School – Sharkia Governorate from 2010 to 2011. They were subdivided into three groups: Group (A): comprised of 31 anemic children. Group (B): comprised of 19 microcytic children. Group (C): comprised the control group of 50 apparently healthy children with normal CBC. All subjects were subjected to: full history taking, thorough clinical examination and iron studies including: serum iron , total iron binding capacity, serum ferritin and transferrin saturation. Results: There was a significant difference among studied subjects in height, presence of anorexia and pallor. Moreover, there was a significant difference among studied subjects in Hb, RBCs count, MCH, RDW (p < 0.001) and WBCs count (p= 0.004). We noticed a significant positive correlation between MCV (fl) and serum iron (mg/dl) in anemic subjects. Also there was a significant positive correlation between MCV (fl) and TIBC (μg/dl) in anemic subjects as well as a significant positive correlation between MCV (fl) and serum ferritin (μg/dl). In microcytic subjects, we found a significant positive correlation between MCV (fl) and iron (mg/dl) and a significant positive correlation between MCV (fl) and ferritin (μg/dl). Conclusion: Every child with clinical manifestations of anemia proved by CBC who have microcytosis and low MCV should undergo iron studies ( serum iron, serum ferritin, total iron binding capacity and transferrin saturation ). Keywords: Iron deficiency , anemia, children.

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assessment of mean corpuscular volume as a surrogate marker for detecting early iron deficiency among school children

background: the aim of the present study was to assess the mean corpuscular volume (mcv) as a surrogate marker for detecting early iron deficiency prior to definitive investigation and treatment. materials and methods: this study was done on one hundred students in swada preparatory school – sharkia governorate from 2010 to 2011. they were subdivided into three groups: group (a): comprised of 3...

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عنوان ژورنال

دوره 3  شماره None

صفحات  61- 68

تاریخ انتشار 2011-08

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